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LLY
Eli Lilly and Company · Healthcare
$1,121.36
-7.62% this month
VERSUS
⟷
COMPARE
ABBV
AbbVie Inc. · Healthcare
$245.10
-6.12% this month
Scoreboard verdict
Across AI score, momentum, valuation, upside, operating margin
LLY
4
ABBV
1
Comparison scoreboard
LLY LEADS 4/5AI Score
LLY ✓74.7
ABBV 52.7
1Y Return
LLY ✓+47.10%
ABBV +25.55%
Fwd P/E
LLY 25.50
ABBV ✓15.45
Target Up.
LLY ✓+11.15%
ABBV +7.75%
Op. Margin
LLY ✓49.39%
ABBV 39.57%
Metrics last refreshed: 8/4/2026
Quick take
LLY vs ABBV: Eli Lilly vs AbbVie Stock Comparison: AI Score, Valuation, Performance and Upside
Eli Lilly is the GLP-1 growth juggernaut with the fastest-growing drug franchise in pharma history and massive obesity market expansion potential. AbbVie is a diversified pharma company navigating the Humira-to-Skyrizi/Rinvoq transition with a high dividend yield and broader therapeutic area exposure. Lilly has superior growth; AbbVie has better income and diversification.
Use this LLY vs ABBV comparison to evaluate two pharma investment approaches. Eli Lilly offers concentrated GLP-1/obesity growth at a premium valuation; AbbVie offers diversified pharma income with strong immunology growth at a more moderate valuation.
Live analysis · updated 8/4/2026
LLY holds the edge across 4 of 5 key metrics in this comparison. LLY has delivered stronger 1-year price return (+47.10% vs +25.55%), though ABBV has the better forward P/E setup (15.45x vs 25.50x for LLY). LLY leads on both revenue growth (55.50%) and operating margin (49.39%), suggesting a stronger fundamental setup on both dimensions. Analyst consensus implies meaningfully more upside for LLY (+11.15%) than for ABBV (+7.75%).
Normalized 1Y performance
LLY
ABBV
Recent returns
LLY
ABBV
Analyst price targets & sentiment
LLY · 27 analysts
STRONG BUYHOLDSTRONG SELL
Buy (1.8/5.0)
Price target range
analyst low$650.00
analyst mean$1,276.96
current price$1,121.36
+11.2% upside to analyst mean
ABBV · 27 analysts
STRONG BUYHOLDSTRONG SELL
Buy (2.0/5.0)
Price target range
analyst low$170.00
analyst mean$270.39
current price$245.10
+7.8% upside to analyst mean
Who should consider this stock?
LLY may suit investors who:
- →Want exposure to the GLP-1/obesity megatrend through the market-leading tirzepatide franchise
- →Believe the obesity drug market TAM is large enough to justify Eli Lilly's premium valuation
- →Value Lilly's pipeline optionality in Alzheimer's, oncology, and next-generation oral GLP-1 formulations
- →Are comfortable with a growth-stock valuation for a pharmaceutical company
ABBV may suit investors who:
- →Prefer a diversified pharma company with exposure across immunology, aesthetics, neuroscience, and oncology
- →Value AbbVie's high dividend yield and Dividend Aristocrat status for income-oriented portfolios
- →Believe Skyrizi and Rinvoq can fully replace and exceed Humira revenue over the next several years
- →Want pharma exposure at a more moderate valuation with better near-term income generation
Performance & AI score
| Metric | LLY | ABBV |
|---|---|---|
| AI score | 74.7 | 52.7 |
| AI rank | #21 | #328 |
| Latest close | $1,121.36 | $245.10 |
| 1M return | -7.62% | -6.12% |
| 6M return | +7.40% | +8.62% |
| 1Y return | +47.10% | +25.55% |
$10,000 invested — hypothetical growth (dividends reinvested)
How much would $10,000 be worth today if invested at the start of each period, with all dividends reinvested?
| Period | LLY | ABBV |
|---|---|---|
| 1Y ago | $14.58K (+45.8%) started 2025-08-04 | $12.43K (+24.3%) started 2025-08-04 |
| 5Y ago | $46.02K (+360.2%) started 2021-08-05 | $28.73K (+187.3%) started 2021-08-05 |
| 10Y ago | $189.49K (+1794.9%) started 2016-08-05 | $83.48K (+734.8%) started 2016-08-05 |
Hypothetical — past performance does not guarantee future results.
Valuation & upside potential
| Metric | LLY | ABBV |
|---|---|---|
| Market cap | $1.05T | $443.36B |
| Trailing P/E | 40.81 | 70.89 |
| Forward P/E | 25.50 | 15.45 |
| Price/Sales | 14.10 | 5.85 |
| EV/Revenue | 14.71 | 7.87 |
| Analyst target | $1,276.96 | $270.39 |
| Target upside | +11.15% | +7.75% |
Growth, profitability & risk
| Metric | LLY | ABBV |
|---|---|---|
| Revenue growth | 55.50% | 10.20% |
| Earnings growth | 169.90% | 290.40% |
| EPS growth | +169.90% | +290.40% |
| FCF margin | +12.67% | +32.32% |
| Operating margin | 49.39% | 39.57% |
| Profit margin | 34.99% | 9.80% |
| ROIC proxy | 107.46% | 6225.00% |
| Return on equity | 107.46% | 6225.00% |
| Dividend yield | 0.60% | 2.76% |
| Beta | 0.51 | 0.28 |
| Debt/equity | 139.01 | 4789.60 |
| Current ratio | 1.50 | 0.80 |
| Quick ratio | 0.72 | 0.52 |
Drawdown & downside risk
Lower drawdown and smaller single-period drops generally indicate a smoother ride, though they do not guarantee lower future risk.
1Y risk snapshot
LLY max drawdown23.31%
ABBV max drawdown19.23%
LLY max wkly drop17.40%
ABBV max wkly drop8.49%
5Y risk snapshot
LLY max drawdown34.48%
ABBV max drawdown21.92%
LLY max wkly drop17.93%
ABBV max wkly drop17.30%
10Y risk snapshot
LLY max drawdown34.48%
ABBV max drawdown45.09%
LLY max wkly drop17.93%
ABBV max wkly drop19.39%
Performance metrics by period
| Period | Metric | LLY | ABBV |
|---|---|---|---|
| 1Y | Growth | +45.82% | +24.30% |
| CAGR | +45.95% | +24.36% | |
| Sharpe ratio | 1.07 | 0.79 | |
| Max drawdown | 23.31% | 19.23% | |
| Max daily drop | 14.14% | 5.20% | |
| Max wkly drop | 17.40% | 8.49% | |
| 5Y | Growth | +341.83% | +145.97% |
| CAGR | +34.63% | +19.74% | |
| Sharpe ratio | 0.94 | 0.70 | |
| Max drawdown | 34.48% | 21.92% | |
| Max daily drop | 14.14% | 12.57% | |
| Max wkly drop | 17.93% | 17.30% | |
| 10Y | Growth | +1504.41% | +433.96% |
| CAGR | +32.00% | +18.24% | |
| Sharpe ratio | 0.92 | 0.61 | |
| Max drawdown | 34.48% | 45.09% | |
| Max daily drop | 14.14% | 16.25% | |
| Max wkly drop | 17.93% | 19.39% |
Business comparison
| Category | LLY | ABBV |
|---|---|---|
| Company | Eli Lilly and Company | AbbVie Inc. |
| Sector | Healthcare | Healthcare |
| Industry | Drug Manufacturers - General | Drug Manufacturers - General |
| Core business | Global pharmaceutical company leading the GLP-1 revolution with Mounjaro (tirzepatide) for diabetes and Zepbound for obesity. Also developing treatments in Alzheimer's, oncology, and immunology. | Global biopharmaceutical company with leading positions in immunology (Skyrizi, Rinvoq), aesthetics (Botox, Juvederm), neuroscience, oncology, and eye care. Navigating the Humira biosimilar transition. |
| Investor focus | Mounjaro/Zepbound prescription growth, manufacturing capacity expansion, obesity market penetration, Alzheimer's drug (donanemab) commercial launch, and pipeline depth. | Skyrizi and Rinvoq growth trajectory post-Humira, aesthetics recovery, neuroscience pipeline, dividend sustainability, and revenue diversification beyond immunology. |
LLY strengths
- →Market-leading GLP-1 franchise — Mounjaro and Zepbound are the fastest-growing drug brands in pharma history
- →Obesity represents a massive TAM expansion — tens of millions of potential patients beyond the diabetes population
- →Strong pipeline with donanemab (Alzheimer's), oncology assets, and next-generation oral GLP-1 formulations
ABBV strengths
- →Skyrizi and Rinvoq are successfully replacing Humira revenue with combined peak sales potentially exceeding Humira's peak
- →Diversified revenue across immunology, aesthetics (Allergan), neuroscience, and oncology provides stability
- →Strong dividend with high yield — AbbVie is a Dividend Aristocrat with a commitment to growing its payout
Risks to watch — LLY
- →Premium valuation (highest P/E among large-cap pharma) requires sustained GLP-1 demand and supply execution
- →Manufacturing capacity constraints for tirzepatide — scaling production to meet demand is a multi-year challenge
- →GLP-1 competition from Novo Nordisk (semaglutide) and emerging oral GLP-1 players could pressure market share
Risks to watch — ABBV
- →Humira biosimilar erosion continues — Skyrizi and Rinvoq must grow fast enough to offset the decline
- →Aesthetics market (Botox, Juvederm) has been softer than expected due to consumer spending headwinds
- →Patent cliffs on key drugs create ongoing need for pipeline replenishment through R&D and M&A
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