APLS vs RETA Comparison: AI Score, Valuation, Performance and Upside
Compare Apellis Pharmaceuticals and rare disease biotech by Syfovre geographic atrophy launch revenue, pegcetacoplan nephrology expansion, and which complement pathway-targeting biotech reaches sustainable commercial revenue first.
Use this Apellis vs Retrophin comparison to evaluate the key differences across valuation, growth, profitability, and risk before making an investment decision.
APLS and RETA are closely matched — they split the tracked metrics evenly.
| Metric | APLS | RETA |
|---|---|---|
| AI score | 41.0 | N/A |
| AI rank | #997 | N/A |
| Latest close | $41.03 | N/A |
| 1M return | +0.45% | N/A |
| 6M return | +107.12% | N/A |
| 1Y return | +150.79% | N/A |
How much would $10,000 be worth today if invested at the start of each period, with all dividends reinvested?
| Period | APLS | RETA |
|---|---|---|
| 1Y ago | $25.08K (+150.8%) started 2025-05-15 | N/A |
| 5Y ago | $7.73K (-22.7%) started 2021-05-17 | N/A |
| 10Y ago | $29.24K (+192.4%) started 2017-11-09 | N/A |
Hypothetical — past performance does not guarantee future results.
| Metric | APLS | RETA |
|---|---|---|
| Market cap | $5.25B | N/A |
| Trailing P/E | 38.35 | N/A |
| Forward P/E | -130.55 | N/A |
| Price/Sales | 4.75 | 2963.20 |
| EV/Revenue | 4.82 | N/A |
| Analyst target | $40.92 | N/A |
| Target upside | -0.26% | N/A |
| Metric | APLS | RETA |
|---|---|---|
| Revenue growth | 60.90% | N/A |
| Earnings growth | N/A | N/A |
| EPS growth | N/A | N/A |
| FCF margin | -5.76% | N/A |
| Operating margin | N/A | N/A |
| Profit margin | 12.06% | N/A |
| ROIC proxy | 46.02% | N/A |
| Return on equity | 46.02% | N/A |
| Dividend yield | N/A | N/A |
| Beta | -0.25 | 1.75 |
| Debt/equity | 114.66 | N/A |
| Current ratio | 3.63 | N/A |
| Quick ratio | 3.00 | N/A |
Lower drawdown and smaller single-period drops generally indicate a smoother ride, though they do not guarantee lower future risk.
| Period | Metric | APLS | RETA |
|---|---|---|---|
| 1Y | Growth | +150.79% | N/A |
| CAGR | +150.95% | N/A | |
| Sharpe ratio | 1.06 | N/A | |
| Max drawdown | 43.53% | N/A | |
| Max daily drop | 31.01% | N/A | |
| Max wkly drop | 33.61% | N/A | |
| 5Y | Growth | -22.67% | N/A |
| CAGR | -5.02% | N/A | |
| Sharpe ratio | 0.27 | N/A | |
| Max drawdown | 82.47% | N/A | |
| Max daily drop | 37.92% | N/A | |
| Max wkly drop | 60.18% | N/A | |
| 10Y | Growth | +192.44% | N/A |
| CAGR | +13.44% | N/A | |
| Sharpe ratio | 0.46 | N/A | |
| Max drawdown | 82.47% | N/A | |
| Max daily drop | 37.92% | N/A | |
| Max wkly drop | 60.18% | N/A |
| Category | APLS | RETA |
|---|---|---|
| Company | APLS | RETA |
| Sector | N/A | N/A |
| Industry | N/A | N/A |
| Core business | N/A | N/A |
| Investor focus | N/A | N/A |
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